HIV-1 Pathogenesis and the GI Tract: The Effects of Colorectal Immune Deficiency and Reconstitution

Saurabh Mehandru, MD
Assistant Professor, Mount Sinai School of Medicine
Visiting Scientist, The Aaron Diamond AIDS Research Center, New York, NY

CME VIDEOTop of page

Learning Objectives:Top of page

At the completion of this educational session, participants should be able to:

  • Understand the functional and anatomic organization of the GI immune system and its relevance to the pathogenesis of HIV-1 infection.
  • Appreciate the impact of acute and chronic HIV-1 on the GI immune system.
  • Know the effect of prolonged antiretroviral therapy on GI immune reconstitution and its potential clinical implications.

About the Presenter:Top of page

Saurabh Mehandru is an Assistant Professor of Gastroenterology at the Mount Sinai School of Medicine in New York City. Saurabh’s research interests include study of the gastrointestinal immune system in HIV infection. He trained at the Aaron Diamond AIDS Research Center in the laboratory of Dr. Martin Markowitz where he described the early and preferential depletion of GI CD4+ T cells during acute HIV infection and the incomplete reconstitution of intestinal CD4 T cells with ART. Saurabh then worked in the laboratory of Dr. Ralph Steinman, where using novel HIV vaccines, he focused on the generation of intestinal immunity against HIV.

How To Get CMETop of page

To obtain CME credit for this and other PRN programs, please visit the PRN Video Channel at the Clinical Education Initiative (CEI) web site PRN and the Medical Society of the State of New York (MSSNY) jointly sponsor PRN enduring materials for CME, and provide them at no cost to the AIDS Institute of the New York State Department of Health (NYSDOH) for broadcast through the CEI. We thank the NYSDOH for making our CME programs available to a wider audience, and hope you will also browse the many other educational opportunities offered by the CEI.



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